This meta-analysis demonstrates that a negative high-sensitivity cardiac troponin measured at least 3 hours after symptom onset in association with an EKG with no evidence of ischemia or injury can effectively rule out an acute myocardial infarction (AMI).

Chest pain is a leading cause of ED admissions and hospital admissions. This meta-analysis isolates certain risk factors and prognostic scoring systems that are best at predicting whether chest pain represents ACS

A multidisciplinary group from 13 major organizations provides consensus recommendations on the appropriate radiologic imaging guidelines for four clinical scenarios presenting as chest pain in the ED.