Articles in "surgical bleeding"

Transexamic Acid Reduces Transfusions and Mortality in Major Bleeding

by Joseph Esherick, M.D., FAAFP, FHM

Now there are two studies that have proven benefit for transexamic acid (TXA) in major trauma. The UK-based CRASH-2 trial showed that TXA saves lives after trauma. A new meta-analysis that analyzed over 10,000 patients also shows that TXA reduces transfusion requirements by 1/3 and showed a trend towards reduced mortality (risk ratio = 0.67, (0.43 to 1.09; P=0.11).